Afar Region Health Atlas, 2021 presents key results from EPHI and IHME collaborative subnational burden of disease analysis as part of the Global Burden of Disease Study 2019 for Afar, a region of Ethiopia. All-cause mortality in Afar reduced from about 3,410 per 100,000 persons in 1990 to about 1,350 per 100,000 persons in 2019. The number of DALYs has significantly reduced from about 1 million DALYs in 1990 to 700 thousand in 2019. Total fertility declined from 6.6 births per woman in 1990 to 5 births per woman in 2019, a 25% change. Of the leading causes of YLLs and YLDs in Afar in 2019, Diarrheal diseases, Neonatal encephalopathy due to birth asphyxia and trauma and Drug-susceptible tuberculosis are the leading three causes. The figure above illustrates leading disease with DALYs attributable to air pollution, child and maternal malnutrition, dietary risks, high systolic blood pressure, and unsafe water, sanitation, and handwashing in Afar. Child and maternal malnutrition is the source of the greatest number of attributable DALYs, followed by Air pollution. The life expectancy in Afar increased from 37 years in 1980 to 64 years in 2019. Afar region population will live, on average, 56 healthy years, with 8 years lived with disability.