Oromia Region Health Atlas, 2021 presents key results from EPHI and IHME collaborative subnational burden of disease analysis as part of the Global Burden of Disease Study 2019 for Oromia region, a regional state of Ethiopia. All-cause mortality in Oromia reduced from about 2,360 per 100,000 persons in 1990 to about 931 per 100,000 persons in 2019. The number of DALYs has significantly reduced from about 20,000,000 DALYs in 1990 to 10,000,000 in 2019. Total fertility declined from 7.3 births per woman in 1990 to 5 births per woman in 2019, a 32% change. Of the leading causes of YLLs and YLDs in Oromia in 2019, Diarrheal diseases, Neonatal encephalopathy due to birth asphyxia and trauma and Lower respiratory infections are the leading three causes. The figure above illustrates leading disease with DALYs attributable to air pollution, child and maternal malnutrition, dietary risks, high systolic blood pressure, and unsafe water, sanitation, and handwashing in Oromia. Child and maternal malnutrition is the source of the greatest number of attributable DALYs, followed by Air pollution. The life expectancy in Oromia increased from 45 years in 1980 to 70 years in 2019. Oromia region population will live, on average, 61 healthy years, with 9 years lived with disability.